Growth impairment in glycogen storage disease type I versus types III/VI/IX: a cross-sectional study.

BMC Pediatr · 2025 · PMC12502152 · PMID 41053679

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.1040

boldest claim

The sentences

highly significantp < 0.001actually significant

Uric Acid (UA) Levels: The mean uric acid level in GSD I patients was significantly higher (431.04 μmol/L) compared to other GSD types (283.79 μmol/L), with a highly significant difference ( p < 0.001).

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marginally non-significantp = 0.104not close (p > 0.1)

IGF1 SDS showed a marginally non-significant positive relationship with height SDS (B = 0.441, p = 0.104), with a standardized Beta of 0.272, suggesting a moderate positive association.

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approached significanceno p-value reported

Glucose levels showed a negative relationship with height SDS (B = −0.439, p = 0.092), which approached significance, but did not meet the conventional threshold.

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did not reach statistical significanceno p-value reported

In combined-cohort regression, lactate was the only independent negative predictor of height SDS ( p = 0.011); glucose levels and IGF1 SDS did not reach statistical significance.

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