A novel anti-PD-L1/IL-8 bispecific antibody BP2402 enhances antitumor immunity and modulates inflammatory signaling in triple-negative breast cancer mice model.

J Transl Med · 2025 · PMC12502168 · PMID 41053808

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showed a trendno p-value reported

CD28 expression, crucial for T cell activation, showed a trend towards higher levels in the BP2402 group (Fig. 7 C).

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did not reach statistical significanceno p-value reported

Interestingly, BP2402 demonstrated slightly greater tumor growth inhibition than the combination therapy, although this difference did not reach statistical significance.

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