Barely Significant
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Conversion Therapy Based on TACE/HAIC-Based Treatment to Improve the Therapeutic Effect of Initially Unresectable Hepatocellular Carcinoma.

Liver Cancer · 2026 · PMC12503740 · PMID 41063738

2
hedged sentences
0.0490
closest p · 1.0× alpha
0.0490
boldest claim

The sentences

borderline significancep = 0.049actually significant
Similarly, tumor size shrinkage showed borderline significance (HR: 1.00, 95% CI: 1.00–1.01, p = 0.049) ( Fig. 7 b) ( Table 5 ).

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did not reach statistical significancep = 0.063so close (0.05 < p ≤ 0.1)
a strong trendno p-value reported
Although radiographic CR did not reach statistical significance (HR: 0.65, 95% CI: 0.41–1.02, p = 0.063), it showed a strong trend toward improved PFS.

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