Routine Monitoring of CAR-T-Cells Expansion and Persistence in Patients With Aggressive Large B-Cell Lymphoma by Flow Cytometry: A Single-Center Experience.

Hematol Oncol · 2025 · PMC12504011 · PMID 41057236

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

a strong trendp = 0.06so close (0.05 < p ≤ 0.1)

In multivariate analysis, no variable retained independent significance, although high TMTV (using the 17.6 cm 3 cutoff) showed a strong trend toward inferior PFS (HR 2.596 [0.953–7.075]; p = 0.06, Table 6A ).

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did not reach statistical significanceno p-value reported

Responders showed higher median peak CAR‐T expansion, although this did not reach statistical significance for 6‐month PFS or OS.

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