Acupuncture improves depressive-like behaviors in CUMS rats by modulating lateral habenula synaptic plasticity via the BDNF/ERK/mTOR pathway.

Mol Brain · 2025 · PMC12505551 · PMID 41063208

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did not reach statistical significanceno p-value reported

In the Sham-AP group, there was an increase in the expression of p-ERK1/2 protein, however, these differences did not reach statistical significance.

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showed a trendno p-value reported

There was no significant improvement in BDNF expression with any treatment, but FLX and EA treatments showed a trend towards enhancing its expression.

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