Barely Significant
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Decreased Mitochondrial DNA Integrity and Elevated Inflammatory Markers in Late-Life Depression: A Longitudinal Study.

Biol Psychiatry Glob Open Sci · 2025 · PMC12506495 · PMID 41069684

Europe PMCDOI
2
hedged sentences
0.0700
closest p · 1.4× alpha
0.0700
boldest claim

The sentences

did not reach statistical significancep = .07so close (0.05 < p ≤ 0.1)
In contrast, the difference in IL-6 levels between groups did not reach statistical significance ( F 58,1 = 3.368, p = .07).

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nominally significantno p-value reported
Notably, we found nominally significant associations between baseline estimated deletion rates and IL-5 and IL-6 levels at the 30-month follow-up, indicating a potential role for ccf-mtDNA integrity in shaping future inflammatory responses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.