EEG-based minimum spanning tree analysis reveals network disruptions in Alzheimer's disease spectrum: an observational study.

Front Aging Neurosci · 2025 · PMC12511049 · PMID 41079997

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did not reach statistical significanceno p-value reported

Eccentricity (χ2 = 6.43, p = 0.040) and Leaf fraction (χ2 = 7.38, p = 0.025) in the beta band showed significant group effects, but post-hoc tests did not reach statistical significance.

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showed a trendno p-value reported

In differentiating MCI-AD from HC, beta band mean PLI showed the strongest discriminatory power (AUC = 0.87, 95% CI: 0.612–0.986, p = 0.0004), whereas theta band Eccentricity showed a trend but did not reach significance (AUC = 0.81, 95% CI: 0.457–0.941, p = 0.0608).

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