Complete resection of brain metastases - when does it matter?

J Neurooncol · 2025 · PMC12511165 · PMID 40844730

Europe PMC DOI

hedged sentences

0.0520

closest p · 1.0× alpha

0.0700

boldest claim

The sentences

a slight trendp = 0.052so close (0.05 < p ≤ 0.1)

TT was used in 23 patients (25.3%) with STR and in 74 patients (16.7%) with GTR with a slight trend toward more TT in the STR group ( p = 0.052).

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showed a trendp = 0.070so close (0.05 < p ≤ 0.1)

However, patients who received CT, showed a trend toward improved survival with GTR (HR: 0.70, 95% CI: 0.48–1.03, p = 0.070).

also in 53,322 other papers

did not reach statistical significanceno p-value reported

A similar trend was observed in patients who received ICI: GTR was associated with a lower risk of death (HR = 0.64, 95% CI: 0.35–1.20, p = 0.167), although the results did not reach statistical significance.

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may be significantno p-value reported

This assumption may be significant when determining the indication of primary surgery for BM and for second-look surgery in selected patients with residual tumors.

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