Previous parity differentially influences cognition in later life depending on dementia status.

In addition, moderation by parity approached significance for the relationship between the diagnoses of NCI compared to MCI for performance on the WMS Delay task ( F (7,340) = 23.831, p < 0.001, R 2 = 0.329, adjusted R 2 = 0.315; Fig. 1c ), such that MCI females with higher parity had reduced performed compared to MCI females with lower parity (β = −0.176, p = 0.067, sr 2 = 0.007), and this was not the case in NCI females (β = −0.080, p = 0.349, sr 2 = 0.002).

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Although only approaching significance, and similar to comparing NCI and DEM females, having more sons was related to reduced performance than having more daughters in MCI, but not in NCI females on the WMS Delay Recall task (model: F (7,284) = 21.890, p < 0.001, R 2 = 0.350, adjusted R 2 = 0.334; β = −0.169 , p = 0.084, sr 2 = 0.007; Fig. 3d ).

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