3D-OCTA Evaluation of Retinal Microcirculation Abnormalities in the Macular Region of Eyes With Anisometropic Amblyopia.

Although pairwise comparisons did not reach statistical significance, previous research has shown that VSD is particularly sensitive to perfusion changes at the capillary level. 26 Yu et al. 27 further demonstrated that, in physiological conditions, macular microvasculature exhibits highly heterogeneous capillary perfusion to meet the elevated energy demands of the densely packed retinal neurons.

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Compared to fellow eyes in anisometropic amblyopia patients, amblyopic eyes showed a trend toward increased VDI across all layers, but differences were not statistically significant ( P = 1), suggesting minimal vascular diameter differences between the two eyes of affected individuals.

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