Similarities and differences in the intestinal actions of metformin and imeglimin.

Specifically, metformin tended to increase the proportion of Lactobacillus , decrease the Lachnospiraceae NK4A136 group, and reduce Alistipes , although these changes did not reach statistical significance due to inter‐individual variability.

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The abundance of the Prevotella in the UCG‐001 group was significantly increased by both drugs, while Bacteroides showed a trend toward an increase (Figure 3C,D ).

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