Significant glomerular IgM deposition predicts poorer kidney outcomes in lupus nephritis compared with other forms of immune complex deposits.

Lupus Sci Med · 2025 · PMC12516977 · PMID 41073109

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0700

boldest claim

The sentences

a clear trendp=0.051so close (0.05 < p ≤ 0.1)

In this subgroup, patients with high glomerular IgM deposition showed a clear trend towards poorer renal survival compared with those with low glomerular IgM deposition (p=0.051), although no significant difference was observed in overall survival (p=0.971).

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did not reach statistical significancep=0.07so close (0.05 < p ≤ 0.1)

While hypertension prevalence appeared higher in the high glomerular IgM deposition group (38.7% vs 32.3%), the difference did not reach statistical significance (p=0.07).

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