Barely Significant
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Neoadjuvant outperforms adjuvant regimens in resectable advanced Chinese melanoma patients: lymph node preservation as a key immunological advantage.

Front Immunol · 2025 · PMC12521139 · PMID 41103416

2
hedged sentences
0.0530
closest p · 1.1× alpha
0.0530
boldest claim

The sentences

a strong trend toward significancep=0.053so close (0.05 < p ≤ 0.1)
This was significantly higher than the observation group (19.2%, p = 0.009, z-test) and showed a strong trend toward significance compared to the adjuvant group (32.1%, p=0.053, z-test).

also in 21 other papers

Numerical improvements over immunotherapy and observation groups did not reach statistical significance, with p-values of 0.120 and 0.073 respectively.

also in 34,328 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.