Single-Stage vs. Multi-Stage Reconstruction in Multi-Ligament Knee Injuries: A Systematic Review and Meta-Analysis of Outcomes and Complications.

J Clin Med · 2025 · PMC12525300 · PMID 41095975

Europe PMC DOI

hedged sentences

0.1250

closest p · 2.5× alpha

0.1250

boldest claim

The sentences

did not reach statistical significancep = 0.125not close (p > 0.1)

Graft failure tended to be higher in single-stage surgery; however this did not reach statistical significance, 3.08% vs. 0.65% OR 4.85 (95% CI 0.67–35.31), p = 0.125.

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showed a trendno p-value reported

However, studies that reported early weightbearing showed a trend toward higher functional scores, though this did not reach the threshold statistical significance (85.7 ± 6.6 vs. 80.4 ± 10.6, p = 0.068).

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a positive trendno p-value reported

Rehabilitation in our analysis did not show a statistically significant effect on outcomes, though early weightbearing did show a positive trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.