Extracellular Vesicles from <i>Escherichia coli</i> Strains of the Gut Microbiota Trigger Hepatic Antioxidant and Anti-Lipogenic Effects via the Gut-Liver Axis in Healthy Neonatal Rats.

Nutrients · 2025 · PMC12525914 · PMID 41097143

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did not reach statistical significanceno p-value reported

At this time point, SOD1 mRNA levels were higher in the group treated with EVs from the probiotic EcN compared to the control and EcoR12-EV-treated groups, although the differences did not reach statistical significance.

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a decreasing trendno p-value reported

By day 16, IL12 and TNFA mRNA levels were comparable between control and EcN-EV-treated animals; however, the expression of COX2 and INOS showed a decreasing trend in animals receiving EcN EVs.

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showed a trendno p-value reported

Furthermore, EVs from the probiotic EcN showed a trend toward reduced TAG levels, although this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Extracellular Vesicles from &lt;i&gt;Escherichia coli&lt;/i&gt; Strains of the Gut Microbiota Trigger Hepatic Antioxidant and Anti-Lipogenic Effects via the Gut-Liver Axis in Healthy Neonatal Rats.

The sentences

Extracellular Vesicles from <i>Escherichia coli</i> Strains of the Gut Microbiota Trigger Hepatic Antioxidant and Anti-Lipogenic Effects via the Gut-Liver Axis in Healthy Neonatal Rats.