Clinical Characteristics of and Treatment Pattern for EGFR-Amplified Colorectal Cancer.

Cancer Res Treat · 2025 · PMC12527622 · PMID 39810491

Europe PMC DOI

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0.1450

closest p · 2.9× alpha

0.1450

boldest claim

The sentences

did not reach statistical significancep=0.145not close (p > 0.1)

OS tended to be better in EGFR amp+ patients (median OS, 76 months; 95% confidence interval [CI], 20.6 to 131.4) than in EGFR amp– patients (median OS, 37 months; 95% CI, 34.9 to 39.1) but the difference did not reach statistical significance (p=0.145) ( Fig. 5A ).

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showed a trendno p-value reported

Univariate analysis of survival outcomes in patients treated with anti-EGFR therapy showed a trend between the absence of EGFR amplification and a higher hazard ratio, though it did not reach statistical significance ( Table 2 ).

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