Altered Coding of Environmental Boundaries in Human Aging: An fMRI Study.

Hippocampus · 2025 · PMC12529463 · PMID 41099159

Europe PMC DOI

hedged sentences

0.0930

closest p · 1.9× alpha

0.2040

boldest claim

The sentences

did not reach statistical significancep = 0.093so close (0.05 < p ≤ 0.1)

In the subiculum, the age effect was in the same direction as for EC; however, as in the original analysis, it did not reach statistical significance ( β = −0.001, SE = 0.001, p = 0.093), mirroring the results using the whole data from younger adults.

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a numerical trendp = 0.204not close (p > 0.1)

In the subiculum, no predictors reached significance, though boundary bias showed a numerical trend in the expected direction (β = −0.008, p = 0.204, Figure 6d ), and all other covariates were non‐significant (BPI: p = 0.968; age: p = 0.755; MoCA: p = 0.346).

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a weak trendno p-value reported

However, in the subiculum, there was anecdotal evidence for the alternative hypothesis (BF 10 = 1.31 [BF 01 = 0.76]), indicating a weak trend toward boundary‐related modulation that does not constitute strong support for a reliable effect.

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approached significanceno p-value reported

In contrast, no significant age group difference was found in the subiculum ( β = −0.002, SE = 0.001, p = 0.075, Figure 6b ), although the effect approached significance.

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