Spatial and maturity heterogeneity of tertiary lymphoid structures shapes immune microenvironment and progression in prostate cancer.

J Natl Cancer Cent · 2025 · PMC12529619 · PMID 41111928

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.8800

boldest claim

The sentences

did not reach statistical significanceP > 0.05actually significant

Peri-TLS, while showing a trend toward improved outcomes, did not reach statistical significance after adjusting for other factors ( P > 0.05).

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showed a trendP = 0.88not close (p > 0.1)

Although peri‐TLS positive patients showed a trend toward improved survival compared to TLS-negative individuals, the differences were not statistically significant (DFI, P = 0.88; PFI, P = 0.54).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.