Lactate dehydrogenase a is a crucial biomarker that affects the prognosis, chemotherapy effect, and immune infiltration of breast cancer.

BMC Womens Health · 2025 · PMC12535109 · PMID 41107806

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a clear trendno p-value reported

Although significant differences were not observed for OS or DMFS in this subgroup ( P = 0.086 and P = 0.16, respectively), a clear trend of poorer prognosis was evident in patients with high LDHA expression compared to their low-expression counterparts (Fig. 4 D, F).

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did not reach statistical significanceno p-value reported

In this cohort study, elderly patients demonstrated higher serum LDH levels; however, this trend did not reach statistical significance before chemotherapy initiation.

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