The nonlinear relationship between the hepatic steatosis index and the risk of gallstones: A threshold analysis based on the National Health and Nutrition Examination Survey data

J Int Med Res · 2025 · PMC12535658

Europe PMC

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closest p

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a significant trendno p-value reported

Additionally, trend test showed a significant trend between HSI quartiles and gallstone risk, with a p for trend value of <0.001 ( Table 2 ).

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did not reach statistical significanceno p-value reported

The nonlinear p value for men was 0.082, which did not reach statistical significance.

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an increasing trendno p-value reported

The RCS curves for sex and age subgroups showed an increasing trend in the relationship between the HSI and gallstone risk; however, the trends varied across sex and age groups ( Figure 3 ).

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