Although we did not find the same significant interaction at shorter follow‐up intervals (i.e., from baseline to 2‐year follow‐up and from 2‐ to 4‐year follow‐up), the interaction effects were in the same negative direction for most of the WM tracts and were nominally significant from 2‐ to 4‐year follow‐ups in the CGC.
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Family History of Substance Use and Stressful Life Events Impact Adolescent Maturation of Cerebral White Matter.
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The sentences
Linear mixed effect models showed that compared to participants with no changes in SU, participants who first experimented with SU between baseline and 4‐year follow‐up had lower FA at 4‐year follow‐up when controlling for baseline FA in the CGH, which approached significance ( B = −0.051, p uncorrected = 5.2 × 10 −2 ).