Barely Significant
← all excerpts

Macular OCT inner retinal changes reflect CNS involvement in m.3243A>G disease.

BMJ Neurol Open · 2025 · PMC12542527 · PMID 41133266

Europe PMCDOI
2
hedged sentences
0.0620
closest p · 1.2× alpha
0.0780
boldest claim

The sentences

approached significancep=0.062so close (0.05 < p ≤ 0.1)
Thinner RNFL was associated with higher odds of CNS involvement (OR=0.913, p=0.044), as was increasing age (OR=1.109, p=0.025), while heteroplasmy demonstrated a positive association that approached significance (OR=1.036, p=0.062).

also in 8,237 other papers

did not reach statistical significancep=0.078so close (0.05 < p ≤ 0.1)
In addition, a positive correlation was observed between m.3243A>G heteroplasmy and NMDAS scaled scores ( figure 2C ), suggesting that higher heteroplasmy levels are associated with greater disease burden; however, this association also did not reach statistical significance (R2 = 0.078; slope=0.143; p=0.078).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.