Long-term outcomes and toxicity of radiotherapy for WHO Grade II and III meningiomas: a retrospective analysis of 98 patients.

In the analysis of LC, none of the examined covariates reached statistical significance; however, there was a suggestive trend favoring higher radiation doses (> 54 Gy), which was associated with a reduced hazard of local recurrence (HR: 0.549, 95% CI: 0.258–1.164; p = 0.118).

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Dose escalation above 54 Gy showed a trend toward improved local control, and severe late toxicities were exceedingly rare; most treatment-related side effects were low-grade and reversible.

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