Anatomical-biochemical discordance and prognostic role of bone metastases in advanced MTC treated with [¹⁷⁷Lu]Lu-DOTA-TATE.

BMC Cancer · 2025 · PMC12553188 · PMID 41136893

Europe PMC DOI

hedged sentences

0.0580

closest p · 1.2× alpha

0.0690

boldest claim

The sentences

borderline significancep = 0.058so close (0.05 < p ≤ 0.1)

Additionally, average dose per cycle demonstrated borderline significance ( p = 0.058, respectively), suggesting a potential relationship with progression-free survival.

also in 7,017 other papers

showed a trendp = 0.069so close (0.05 < p ≤ 0.1)

Ga-68 uptake also showed a trend toward increased risk (HR: 2.023, p = 0.069), though confidence intervals were wide due to small sample size.

also in 53,322 other papers

did not reach statistical significanceno p-value reported

Longer PFS was also observed in those receiving higher cumulative dose, those with larger solitary tumors, and those treated in the first-line setting, although these trends did not reach statistical significance.

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.