Comparative efficacy and safety of prostacyclin therapies for pulmonary arterial hypertension: a systematic review and network meta-analysis.

Front Med (Lausanne) · 2025 · PMC12554579 · PMID 41158465

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did not reach statistical significanceno p-value reported

However, this difference did not reach statistical significance (RR = 0.85, 95% CI: 0.66 to 1.10).

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showed a trendno p-value reported

In the direct comparison between active treatments presented in the league table, selexipag showed a trend toward greater reduction in clinical worsening compared to treprostinil.

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