Linking Elastin in Skeletal Muscle Extracellular Matrix to Metabolic and Aerobic Function in Type 2 Diabetes: A Secondary Analysis of a Lower Leg Training Intervention.

Metabolites · 2025 · PMC12566085 · PMID 41149633

Europe PMC DOI

hedged sentences

0.0867

closest p · 1.7× alpha

0.0867

boldest claim

The sentences

showed a trendp = 0.0867so close (0.05 < p ≤ 0.1)

The collagen area was elevated in participants with T2D at baseline ( p = 0.0443) and showed a trend toward reduction following a 10-day SLET ( p = 0.0867).

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did not reach statistical significanceno p-value reported

Collagen area showed a downward trend following the 10-day SLET intervention, yet this change did not reach statistical significance when stratified by diabetes status.

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a positive trendno p-value reported

VO 2peak correlated positively with elastin and showed a positive trend with proteoglycans by wheat germ agglutinin staining, while no relationship was observed with collagen area or density.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.