Risk of cataract in patients with systemic lupus erythematosus: a retrospective cohort study in Taiwan.

BMJ Open · 2025 · PMC12570922 · PMID 41145257

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a borderline significant trendno p-value reported

While cumulative glucocorticoid dose was not consistently associated with cataract risk, higher cumulative exposure showed a borderline significant trend toward increased risk (adjusted OR=1.14, 95% CI 0.99 to 1.31).

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showed a trendno p-value reported

Analysis of corticosteroid exposure revealed that cumulative dose showed a trend towards increased risk at high exposure (adjusted OR (aOR) = 1.14, 95% CI 0.99 to 1.31), while average daily dose demonstrated a dose–response effect: 1–5 mg/day (aOR=1.31, 95% CI 1.13 to 1.52) and ≥5 mg/day (OR=2.48, 95% CI 2.16 to 2.86).

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