Barely Significant
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Correlation of immune cell subsets in the tumor microenvironment and peripheral blood with immunotherapy response in esophageal squamous cell carcinoma.

Front Immunol · 2025 · PMC12575347 · PMID 41181122

2
hedged sentences
0.0530
closest p · 1.1× alpha
0.3180
boldest claim

The sentences

did not reach statistical significanceP = 0.053so close (0.05 < p ≤ 0.1)
1.242, P < 0.05), while SELL (CD62L) expression trended higher but did not reach statistical significance (0.441 vs. 0.398, P = 0.053, Figures 4E, F ).

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showed a trendP = 0.318not close (p > 0.1)
Patients with Δ>3.45% showed a trend toward longer PFS compared to those with Δ<3.45% (8.0 vs. 7.0 months; HR = 0.637, 95% CI 0.243–1.671, P = 0.318, Supplementary Figure S3a ).

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