Other variables, including gender, smoking status, TNM stage, anatomical involvement, lymph node involvement, histological differentiation, tumor methylation status, and GABRB2 expression levels (both increased and decreased), did not reach statistical significance in the multivariate model.
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Methylation-Driven downregulation of GABRB2 in oral carcinoma's subtype: implications for early diagnosis and differentiation.
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Similarly, while patients with higher GABRB2 expression showed a trend toward worse overall survival, this association did not reach statistical significance.