A First-in-Human Study of ATM Inhibitor Lartesertib as Monotherapy in Patients with Advanced Solid Tumors.

Clin Cancer Res · 2025 · PMC12580772 · PMID 40875525

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a negative trendno p-value reported

A negative trend was observed in NK cell subsets across all DLs (Supplementary Fig.

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showed a trendno p-value reported

PD analysis showed a trend of reduction of γ-H2AX levels, with highest target inhibition of 80% to 100%.

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