Although GERD itself did not show a significant mediating effect between frailty and depression ( P = .055), the result approached significance, suggesting a potential modest influence.
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The mediating role of dietary habits in the causal relationships between frailty, depression, and gastroesophageal reflux disease.
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The sentences
In the MVMR analysis of the 6 dietary patterns significantly associated with depression, the relationship between frailty and GERD on depression shifted from positive to negative, although the relationship between frailty and depression did not reach statistical significance.