Mutation profile and molecular heterogeneity in mismatch repair deficient endometrial carcinoma.

Front Oncol · 2025 · PMC12583210 · PMID 41195266

Europe PMC DOI

hedged sentences

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

did not reach statistical significancep=0.067so close (0.05 < p ≤ 0.1)

Regarding surgical management, laparoscopic procedure was more frequently performed in dMMR patients (93.2%) compared to pMMR patients (81.4%), though this difference approached but did not reach statistical significance (p=0.067).

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showed a trendno p-value reported

However, the high-TMB group showed a trend toward lower recurrence/metastasis rate (22.2% vs . 44.1%) and mortality (0% vs . 5.9%).

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