Effectiveness of Scalp-cooling Therapy for Preventing Chemotherapy-induced Alopecia in Patients With Breast Cancer: A Prospective Observational Study Focusing on Scalp, Eyebrow, and Eyelash Hair Loss.

Although our results did not reach statistical significance (probably due to the small sample size), they suggest a potential benefit that merits further study.

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Although the differences in eyebrow and eyelash hair loss between the scalp-cooling and control groups were not significant ( p =0.095 and p =0.199, respectively), a clear trend toward reduced severe alopecia was observed in the scalp-cooling group.

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