Barely Significant
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Real-World Off-Label Use of Semaglutide for Weight Reduction: User Behavior, Effectiveness, and Satisfaction.

Patient Prefer Adherence · 2025 · PMC12588353 · PMID 41199795

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showed a trendno p-value reported
Although the differences did not reach statistical significance (presumably due to the small sample sizes), the group that escalated to 1.0 mg showed a trend toward greater cumulative weight loss than the groups that did not escalate to 1.0 mg.

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