Barely Significant
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RNA preservation in human dental pulp for transcriptomic profiling: a comparative multi-parameter study.

Front Dent Med · 2025 · PMC12592039 · PMID 41210154

Europe PMCDOI
2
hedged sentences
0.0780
closest p · 1.6× alpha
0.1000
boldest claim

The sentences

approached significancep = 0.078so close (0.05 < p ≤ 0.1)
The comparison between RNAiso Plus and snap freezing approached significance (mean difference: 0.273, 95% CI: −0.025 to 0.572, p = 0.078), while RNAiso Plus and RNA Later storage showed comparable purity levels (mean difference: −0.063, 95% CI: −0.361 to 0.236, p = 0.865) ( Table 1 ). 3.2.2. 260/230 absorbance ratio analysis for organic contamination The 260/230 absorbance ratio assessment, which reflects potential contamination by organic compounds, salts, and carbohydrates, showed no statistically significant differences among the three preservation methods (one-way ANOVA: F 2,33 = 1.295, p = 0.288, η 2 = 0.073).

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approaching significancep < 0.1so close (0.05 < p ≤ 0.1)
However, the p -value approaching significance ( p < 0.1) suggests a trend toward method-dependent quality differences that may achieve significance with larger sample sizes.

also in 1,619 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.