Neutrophil extracellular traps predict poor response and prognosis in non-small cell lung cancer immunotherapy.

Ther Adv Med Oncol · 2025 · PMC12592660 · PMID 41209618

Europe PMC DOI

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closest p · 1.4× alpha

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boldest claim

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showed a trendp = 0.07so close (0.05 < p ≤ 0.1)

NETs’ levels inversely correlated with CD8 + T-cell density ( R = –0.33, p = 0.025) and showed a trend toward positive correlation with CAFs ( R = 0.27, p = 0.07).

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did not reach statistical significancep = 0.07so close (0.05 < p ≤ 0.1)

NETs showed a trend toward a positive correlation with CAFs Further analysis of the relationship between NETs and CAFs cells revealed a trend of positive correlation between their densities, though this did not reach statistical significance ( R = 0.27, p = 0.07; Figure 4(a) and ( b )).

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