Claudin-4 as a dual regulator of genome stability and immune evasion in high grade serous ovarian cancer.

Sci Rep · 2025 · PMC12603150 · PMID 41214101

Europe PMC DOI

hedged sentences

0.0538

closest p · 1.1× alpha

0.0538

boldest claim

The sentences

did not reach statistical significancep = 0.0538so close (0.05 < p ≤ 0.1)

In OVCAR3 WT cells, Rab7 transfection also led to a clear reduction in type I interferon signaling, though it did not reach statistical significance ( p = 0.0538).

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a clear trendno p-value reported

Quantification of CD3-zeta expression revealed a clear trend of increased type I interferon response in CMP/olaparib-treated cells compared to untreated controls.

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