Visualizing the vascular-cellular microenvironment in lung cancer brain metastasis via multiparametric fusion of DCE-MRI and DWI.

Front Oncol · 2025 · PMC12603911 · PMID 41229500

Europe PMC DOI

hedged sentences

0.0950

closest p · 1.9× alpha

0.0950

boldest claim

The sentences

approaching significancep=0.095so close (0.05 < p ≤ 0.1)

In LUSC-BM, ADC values were positively driven by K trans (β=16.55, p<0.0001) and CER (β=1.941,p=0.005),but negatively associated with Ve(β=−4.685,p=0.008),Vp(β=−16.66,p=0.002),iAUC 90 (β=−49.22,p=0.005),and K ep (β=−1.638, p=0.001), with Max.Slope approaching significance (β=8.903, p=0.095).

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a positive trendno p-value reported

failed to reach statistical significanceno p-value reported

Other parameters, such as ADC value (β=0.002,p=0.305) and K trans (β=0.038,p=0.051), showed a positive trend but failed to reach statistical significance after adjustment.

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