Female Sex is Protective Against MASLD With Clinically Significant Fibrosis in a Large Cross-sectional Cohort of Persons With HIV.

Open Forum Infect Dis · 2025 · PMC12604012 · PMID 41229880

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0700

boldest claim

The sentences

did not reach statistical significanceP = .06so close (0.05 < p ≤ 0.1)

Findings were similar for MASLD-CSF; postmenopausal women had lower odds of MASLD-CSF compared to men (0.43 [0.20–0.96], P = .04) but the comparison between pre-/perimenopausal women and men did not reach statistical significance (0.40 [0.15–1.05], P = .06) ( Supplementary Table 2 ).

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failed to reach statistical significanceP = .07so close (0.05 < p ≤ 0.1)

Though the effect size was similar for pre-/perimenopausal women versus men, this comparison failed to reach statistical significance (0.65 [0.41–1.03], P = .07) ( Supplementary Table 1 ).

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