Investigating the Effects of Different Lengths of Proximal Margin for Siewert Type II and Type III Adenocarcinoma of Esophagogastric Junction on Short- and Long-Term Prognosis.

Cancer Manag Res · 2025 · PMC12604577 · PMID 41230184

Europe PMC DOI

hedged sentences

0.2110

closest p · 4.2× alpha

0.2110

boldest claim

The sentences

did not reach statistical significanceP=0.211not close (p > 0.1)

While the higher rate of locoregional recurrence in the shortest margin group did not reach statistical significance (P=0.211), likely due to the small number of events, it aligns with the higher rates of R1 resection and anastomotic recurrence observed in this group.

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showed a trendno p-value reported

Conversely, for tumors >4 cm or Siewert Type III, a margin >4 cm showed a trend toward better prognosis.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.