European Consensus on Functional Bloating and Abdominal Distension-An ESNM/UEG Recommendations for Clinical Management.

United European Gastroenterol J · 2025 · PMC12606050 · PMID 40844856

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showed a trendno p-value reported

A meta‐analysis of 24 trials found that combinations of bacterial strains showed a trend toward improving in functional bloating, but individual strains like Bifidobacterium , Lactobacillus , and Saccharomyces were not significantly effective [ 69 ].

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did not reach statistical significanceno p-value reported

Pyridostigmine, another cholinesterase inhibitor, showed some efficacy in reducing bloating severity in one study, though the results did not reach statistical significance across groups [ 59 ].

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