Barely Significant
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Pulmo-Cardio-Renal Continuum in Chronic Lung Diseases: A 3-Year Prospective Cohort Study.

J Clin Med · 2025 · PMC12608822 · PMID 41227028

Europe PMCDOI
2
hedged sentences
0.0400
closest p · 0.8× alpha
0.0400
boldest claim

The sentences

approached significancep = 0.04actually significant
The between-group difference at 2025 approached significance with a small-to-moderate effect ( p = 0.04; q = 0.06; δ ≈ 0.28–0.30).

also in 6,004 other papers

a negative trendno p-value reported
In subprofile C1, a negative trend was observed in COPD patients, largely due to an increase in sPAP, particularly by the third year of follow-up.

also in 2,741 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.