Profibrotic Biomarkers Correlate with Clinical Presentation and Outcome in Cardiac Transthyretin Amyloidosis.

As shown in Supplementary Figure S5 , patients receiving tafamidis showed a trend toward improved outcomes for the combined endpoint and the endpoint death/htx ( p = 0.19).

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As patients with ATTRv-CA were assigned half to Cluster 1 and 2, we confirmed the survival prediction force of our clusters in this subgroup and found stable highly significant differences in the Kaplan–Meier curves of this subgroup (see Figure 4 F).

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While the effect did not reach statistical significance, Kaplan–Meier analyses demonstrated a favorable separation of survival curves for tafamidis-treated patients.

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