Early risk factors for acute chest syndrome in sickle cell anemia: A pediatric study.

PLoS One · 2025 · PMC12617906 · PMID 41237095

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp ≤ 0.0001actually significant

Adjusted means showed the same stepwise increase (77.1, 85.4, and 89.4 fL, respectively), with all pairwise contrasts being highly significant (p ≤ 0.0001).

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did not reach statistical significancep = 0.066so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Opiate use in the ED showed a trend towards increased risk, though it did not reach statistical significance (OR 3.46, 95% CI 0.92–13.0, p = 0.066).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.