Barely Significant
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Novel Chewable Pleuran-Based Supplement Decreases Respiratory Tract Infections in Children: A Randomised Controlled Trial.

Adv Ther · 2025 · PMC12618377 · PMID 41085920

2
hedged sentences
0.2250
closest p · 4.5× alpha
0.3430
boldest claim

The sentences

showed a trendP = 0.225not close (p > 0.1)
Analysis of individual RTI subtypes showed a trend toward shorter duration of common cold (8.88 ± 8.79 vs. 10.32 ± 8.57; P = 0.225) and tonsillopharyngitis (1.88 ± 4.12 vs. 2.67 ± 4.74; P = 0.186) in the active group (Table 2 ).

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did not reach statistical significanceP = 0.343not close (p > 0.1)
Although the mean duration of total RTIs was shorter in children given the pleuran-based supplement compared to those receiving the active placebo, the difference did not reach statistical significance (15.17 ± 10.13 vs. 16.60 ± 11.88; P = 0.343).

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