Serum Levels of Alpha7 Nicotinic Acetylcholine Receptor and Their Association With Cardiovascular Autonomic Function Tests in Healthy Young Adults.

Cureus · 2025 · PMC12619949 · PMID 41250705

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0640

boldest claim

The sentences

a negative trendp = 0.053so close (0.05 < p ≤ 0.1)

A negative trend was observed between alpha7 nAChR and BMI (ρ = -0.35, 95% CI: -0.61 to 0.01, p = 0.053), though this did not reach statistical significance.

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did not reach statistical significancep = 0.062so close (0.05 < p ≤ 0.1)

Conversely, men showed slightly higher sympathetic indicators such as LF/HF ratio and LF normalized units, though these differences did not reach statistical significance (LF/HF median difference = -0.32, 95% CI: -0.68 to 0.02, p = 0.062; LF nu = -11.45, 95% CI: -24.19 to 0.59, p = 0.062).

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a nonsignificant trendp = 0.064so close (0.05 < p ≤ 0.1)

For DBP, gender remained a significant predictor, F(1, 30) = 12.88, p = 0.001, explaining around 30% of the variance, while BMI showed a nonsignificant trend, F(1, 30) = 3.69, p = 0.064, accounting for about 11%.

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