Adolescent mice exhibit lower reward sensitivity than adults.

When preference, excluding sex as a factor, was categorized as a binary outcome ( Figure 3D ), cumulative frequency analysis showed a trend toward an age effect ( Figure 3E , χ 2 (1) = 3.795, p = 0.051).

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While post hoc comparisons did not reach statistical significance, a trend toward lower social preference in late-adolescents compared to adults was observed.

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