Induction chemotherapy followed by definitive chemoradiation in patients with inoperable esophageal squamous cell carcinoma: a multicenter retrospective study.

Discov Oncol · 2025 · PMC12627277 · PMID 41251837

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showed a trendno p-value reported

A similar pattern was observed for clinical TNM stage, where CT-CRT showed a trend toward improved DFS in advanced stages (III-IV), with an HR of 0.550 (95% CI: 0.301–1.005), but no significant effect in earlier stages (I–II), with an HR of 1.128 (95% CI: 0.437–2.911).

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did not reach statistical significanceno p-value reported

The addition of IC (HR: 0.735, 95% CI: 0.395–1.368, p = 0.332) demonstrated a trend toward improved DFS, though it did not reach statistical significance (Table 2 ).

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