Effect of type 1 diabetes on the inflammatory response in periodontal disease.

Front Immunol · 2025 · PMC12631499 · PMID 41280935

Europe PMC DOI

hedged sentences

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantp < 0.0001actually significant

Specifically, the reduction in TNFα was significant only in the gingivitis subgroup ( p = 0.02), while IFNγ showed a consistent and highly significant decrease across all stages of periodontal disease ( p < 0.0001 for all comparisons).

also in 132,142 other papers

did not reach statistical significancep = 0.069so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

TGF-β1 levels showed a trend toward elevation in T1DM patients across all periodontal conditions; however, these differences did not reach statistical significance (F (1, 126) = 4.029 and p = 0.069; Figure 2G ).

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.