Barely Significant
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Synthesis and preliminary biological evaluation of quinoline-chrysin hybrids against head and neck squamous cell carcinoma.

Sci Rep · 2025 · PMC12635337 · PMID 41266746

Europe PMCDOI
2
hedged sentences
0.1900
closest p · 3.8× alpha
0.1900
boldest claim

The sentences

did not reach statistical significancep = 0.19not close (p > 0.1)
Notably, a slight reduction in TP53 expression compared to control was detected following treatment with compound 16 at 10 μM, although this change did not reach statistical significance ( p = 0.19).

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failed to reach statistical significancep = 0.33not close (p > 0.1)
a decreasing trendno p-value reported
A decreasing trend was observed for compound 16 at 20 μM compared to control, consistent with findings in the FaDu cell line, but this effect also failed to reach statistical significance ( p = 0.33).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.